Papilomaviry (HPV) u homosexuálů

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Pavel Čermák

Lidské papilomaviry jsou zodpovědné za 90 – 99 % případů rakoviny děložního čípku a 70 – 100 % případů rakoviny konečníku.

Jejich genetická informace je kódovaná v DNA a jsou známé pod anglickou zkratkou HPV (Human papillomavirus).

Dnes jsou zmapované genetické sekvence více než 170 typů lidských papilomavirů, které se dělí do pěti rodů: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus Nupapillomavirus.

Kromě toho bylo zjištěno přinejmenším dalších 200 domnělých typů virů, které teprve čekají na zmapování svého genomu a klasifikaci.

Wikipedie nabízí následující přehled onemocnění způsobených papilomaviry a u nich vždy čísla typů , které je vyvolávají:

 

Onemocnění

Typ HPV

Common warts

2, 7, 22

Plantar warts

1, 2, 4, 63

Flat warts

3, 10, 8

Anogenital warts

6, 11, 42, 44 and others[13]

Anal dysplasia (lesions)

6, 16, 18, 31, 53, 58[14]

Genital cancers

  • Highest risk:[13] 16, 18, 31, 45
  • Other high-risk:[13][15] 33, 35, 39, 51, 52, 56, 58, 59
  • Probably high-risk:[15] 26, 53, 66, 68, 73, 82

Epidermodysplasia verruciformis

more than 15 types

Focal epithelial hyperplasia (oral)

13, 32

Oral papillomas

6, 7, 11, 16, 32

Oropharyngeal cancer

16

Verrucous cyst

60

Laryngeal papillomatosis

6, 11

 

DNA papilomavirů však byla zjištěna také v periferní krvi u 8,3 % zdravých dárců krve.

V další studii (Carlo Foresta) byly bílkoviny HPV nalezeny v lymfocytech Cd20+ a Cd56+ v periferní krvi a spermatu. Nález souvisel s infekcí spermatu papilomavirem typu 16.

Informace o nepřehledném počtu typů lidských papilomavirů a jejich výskytu v různých typech lidských tkání zde uvádím úmyslně, aby bylo jasné, o jak složitou problematiku se jedná a kolik toho ještě zbývá prozkoumat, protože jednotlivé typy virů se geneticky i chováním v organismu poměrně výrazně liší.

Nechci však vyvolávat paniku. S papilomaviry se během života setká každý a velká část z nich je pokládána za neškodné. Lidský organismus se jich většinou dokáže po infekci zbavit sám a vážné onemocnění způsobí jen v některých případech.

Na druhé straně se však nejedná o zanedbatelnou problematiku, jak vidíme z mohutné kampaně podporující očkování proti některým typům papilomavirů. Základní informaci o papilomavirech je možné nalézt například v článku, který napsal MUDr Fait.  http://www.hpv-guide.cz/clanek-mudr-tomas-fait-phd-co-dokazi-lidske-papilomaviry

Papilomaviry u homosexuálů

Výskytem papilomavirové infekce u mužů kteří mají sex s muži (MSM) se zabývá studie, kterou publikoval Stephen Goldstone a další autoři. Průměrný věk byl 22 let a do studie byli úmyslně vybráni muži, kteří nebyli nakaženi HIV (virem AIDS).

Přítomnost typů papilomavirů 6, 11, 16 nebo 18 byla zjištěna u 30 % MSM (mužů kteří mají sex s muži) v porovnání s 8 % heterosexuálních mužů. Tato studie pracovala s mladými muži o průměrném věku 22 let a tak je počet nakažených relativně nízký v porovnání s jinými studiemi.

Peter Newman a spoluautoři provedli metaanalýzu více studií a uvádějí, že anální infekce papilomaviry se vyskytuje u 15 % heterosexuálních mužů, 60 % MSM kteří jsou HIV negativní a téměř 95 % MSM HIV+ (mužů kteří mají sex s muži a jsou nakaženi virem působícím AIDS).

Vysoký výskyt anální infekce HPV souvisí se zvýšeným výskytem rakoviny konečníku, který je u MSM 44krát vyšší, než v běžné populaci. V případě MSM, kteří jsou nakaženi HIV je výskyt rakoviny konečníku dokonce 60krát vyšší.

Infekce papilomaviry, které patří k nejrozšířenějším původcům sexuálně přenosných nemocí, se tedy vyskytuje přibližně čtyřikrát častěji u mužů, kteří mají sex s muži, než u heterosexuálních mužů. Z toho vyplývají podobná varování jako u jiných pohlavních nemocí. Toto varování se týká v první řadě všech mužů, kteří mají někdy sex s jiným mužem (MSM). Týká se však také žen, které by měly být zvláště ostražité kdykoli mají podezření, že muž který o ně projevuje zájem je homosexuál, bisexuál, nebo má někdy homosex za peníze. Důsledky jsou jasné i pro případné dárcovství krve nebo jiných orgánů homosexuály.

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СПРАВЕДЛИВАЯ РОССИЯ в Севастополе пообещала "разгромить" антинародную "Единую Россию"


СПРАВЕДЛИВАЯ РОССИЯ в Севастополе презентовала "третий путь" и пообещали "разгромить" антинародную "Единую Россию"






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СПРАВЕДЛИВАЯ РОССИЯ в Севастополе презентовала "третий путь" и пообещали "разгромить" антинародную "Единую Россию"
Руководство и актив севастопольской региональной организации политической партии СПРАВЕДЛИВАЯ РОССИЯ провели в рамках Всероссийской информационной акции пресс-конференцию в зале гостиницы "Украина".

Большое количество присутствующих журналистов и съемочных групп телеканалов, а также представителей органов власти свидетельствовали об интересе в Севастополе к позиции и деятельности СПРАВЕДЛИВОЙ РОССИИ.

Журналисты отметили, что лидеры справедливороссов, которые сейчас все более позиционируют себя как российские социал-демократы, были настроены оптимистично и решительно.

Основной темой встречи были инициативы СПРАВЕДЛИВОЙ РОССИИ в Государственной Думе, направленные на построение справедливого социального государства, и блокирование этих нужных законопроектов парламентским большинством из партии "Единая Россия".

Лидер севастопольских справедливороссов Евгений Дубовик отметил, что сегодня 72% севастопольцев негативно относится к сложившейся политической системе страны из-за продолжающегося в течение пяти лет падения уровня жизни россиян. Он заявил, что "Единая Россия" сегодня не является "партией президента", а, напротив, выступает против социальной политики Владимира Путина и против народа!

Член бюро регионального отделения Валентин Дьяченко рассказал, какие важнейшие проекты СПРАВЕДЛИВОЙ РОССИИ "отправила в архив" главенствующая фракция "Единой Росии". Среди них – введение прогрессивного налога, двукратное увеличение пенсии после 70 лет и запрет на повышение пенсионного возраста, выплата ежегодной 13-ой пенсии, ограничение размера платы за коммунальные услуги, увеличение оплачиваемого декретного отпуска с 1,5 до 3 лет,

При этом, даже при мощнейшем противодействии со стороны депутатов от ЕР, СПРАВЕДЛИВАЯ РОССИЯ является второй в парламенте по числу принятых законопроектов.

Депутат Нахимовского муниципального округа Дмитрий Белогорцев также подчеркнул, что в то время как Президент России Владимир Путин говорит о "сбережении народа", "единороссы" в законодательной власти последовательно препятствуют принятию законов, направленных на народосбережение.

Депутат привел примеры работы местных чиновников – на 90% своих запросов он получает "формальные отписки". А незаконную стройку в районе дома №29 по Проспекту Победы в Нахимовском районе власти не могут остановить, потому что... застройщик не становился на учет.

Кандидат философских наук, Научный руководитель Центра муниципальной подготовки Института экономики и права Академии труда и социальных отношений, депутат многих созывов Городского совета Севастополя Владимир Чекмезов ярко и образно охарактеризовал ситуацию с использованием природных богатств России. При том, что наша страна имеет самые богатые недра, около 20 миллионов россиян по-прежнему находятся на уровне бедности. Причина в том, что "Единая Россия" отстаивает интересы не народа, а является "сторожевой собакой" олигархов, препятствуя справедливому распределению доходов страны и реализации на деле принципа построения социального государства.

Ученый призвал "загнать в будку" этого "сторожевого пса" в ходе выборов, лишив "Единую Россию" народных голосов.

Депутат нескольких созывов севастопольского городского совета, работник сферы образования и науки Татьяна Ульянова заявила о том, что сегодня социал-демократы в России – партия СПРАВЕДЛИВАЯ РОССИЯ – предлагают "третий путь" – не построение капитализма в интересах олигархов и не утопические попытки строительства коммунизма, а строительство социально ориентированного государства. Именно такие социальные ориентиры намечены в Послании Президента России Владимира Путина.

Союзником социал-демократов России Татьяна Ульянова назвала профсозы страны, социально ориентированные и просветительские организации.

Евгений Дубовик пообещал занять большинство мест в следующем составе Законодательного собрания. Он сообщил, что не верит в опросы общественного мнения, и заверил, что когда люди узнают об инициативах его партии и действиях "Единой России" в парламенте страны, то "все проценты рухнут", а позиции "единороссов" "будут разгромлены".

Евгений Дубовик подчеркнул, что СПРАВЕДЛИВАЯ РОССИЯ в Севастополе идет на выборы под своим флагом, и не будут объединяться на местном уровне с другими политическими силами, но готовы выдвигать известных в городе беспартийных общественников.


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