Papilomaviry (HPV) u homosexuálů

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25.03.2014 [01:14], pacer, Pohlavní nemoci, komentováno 395543×, zobrazeno 11847206×

Pavel Čermák

Lidské papilomaviry jsou zodpovědné za 90 – 99 % případů rakoviny děložního čípku a 70 – 100 % případů rakoviny konečníku.

Jejich genetická informace je kódovaná v DNA a jsou známé pod anglickou zkratkou HPV (Human papillomavirus).

Dnes jsou zmapované genetické sekvence více než 170 typů lidských papilomavirů, které se dělí do pěti rodů: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus a  Nupapillomavirus.

Kromě toho bylo zjištěno přinejmenším dalších 200 domnělých typů virů, které teprve čekají na zmapování svého genomu a klasifikaci.

Wikipedie nabízí následující přehled onemocnění způsobených papilomaviry a u nich vždy čísla typů , které je vyvolávají:

 

Onemocnění

Typ HPV

Common warts

2, 7, 22

Plantar warts

1, 2, 4, 63

Flat warts

3, 10, 8

Anogenital warts

6, 11, 42, 44 and others[13]

Anal dysplasia (lesions)

6, 16, 18, 31, 53, 58[14]

Genital cancers
  • Highest risk:[13] 16, 18, 31, 45
  • Other high-risk:[13][15] 33, 35, 39, 51, 52, 56, 58, 59
  • Probably high-risk:[15] 26, 53, 66, 68, 73, 82

Epidermodysplasia verruciformis

more than 15 types

Focal epithelial hyperplasia (oral)

13, 32

Oral papillomas

6, 7, 11, 16, 32

Oropharyngeal cancer

16

Verrucous cyst

60

Laryngeal papillomatosis

6, 11

 

DNA papilomavirů však byla zjištěna také v periferní krvi u 8,3 % zdravých dárců krve.

V další studii (Carlo Foresta) byly bílkoviny HPV nalezeny v lymfocytech Cd20+ a Cd56+ v periferní krvi a spermatu. Nález souvisel s infekcí spermatu papilomavirem typu 16.

Informace o nepřehledném počtu typů lidských papilomavirů a jejich výskytu v různých typech lidských tkání zde uvádím úmyslně, aby bylo jasné, o jak složitou problematiku se jedná a kolik toho ještě zbývá prozkoumat, protože jednotlivé typy virů se geneticky i chováním v organismu poměrně výrazně liší.

Nechci však vyvolávat paniku. S papilomaviry se během života setká každý a velká část z nich je pokládána za neškodné. Lidský organismus se jich většinou dokáže po infekci zbavit sám a vážné onemocnění způsobí jen v některých případech.

Na druhé straně se však nejedná o zanedbatelnou problematiku, jak vidíme z mohutné kampaně podporující očkování proti některým typům papilomavirů. Základní informaci o papilomavirech je možné nalézt například v článku, který napsal MUDr Fait.  http://www.hpv-guide.cz/clanek-mudr-tomas-fait-phd-co-dokazi-lidske-papilomaviry

Papilomaviry u homosexuálů

Výskytem papilomavirové infekce u mužů kteří mají sex s muži (MSM) se zabývá studie, kterou publikoval Stephen Goldstone a další autoři. Průměrný věk byl 22 let a do studie byli úmyslně vybráni muži, kteří nebyli nakaženi HIV (virem AIDS).

Přítomnost typů papilomavirů 6, 11, 16 nebo 18 byla zjištěna u 30 % MSM (mužů kteří mají sex s muži) v porovnání s 8 % heterosexuálních mužů. Tato studie pracovala s mladými muži o průměrném věku 22 let a tak je počet nakažených relativně nízký v porovnání s jinými studiemi.

Peter Newman a spoluautoři provedli metaanalýzu více studií a uvádějí, že anální infekce papilomaviry se vyskytuje u 15 % heterosexuálních mužů, 60 % MSM kteří jsou HIV negativní a téměř 95 % MSM HIV+ (mužů kteří mají sex s muži a jsou nakaženi virem působícím AIDS).

Vysoký výskyt anální infekce HPV souvisí se zvýšeným výskytem rakoviny konečníku, který je u MSM 44krát vyšší, než v běžné populaci. V případě MSM, kteří jsou nakaženi HIV je výskyt rakoviny konečníku dokonce 60krát vyšší.

Infekce papilomaviry, které patří k nejrozšířenějším původcům sexuálně přenosných nemocí, se tedy vyskytuje přibližně čtyřikrát častěji u mužů, kteří mají sex s muži, než u heterosexuálních mužů. Z toho vyplývají podobná varování jako u jiných pohlavních nemocí. Toto varování se týká v první řadě všech mužů, kteří mají někdy sex s jiným mužem (MSM). Týká se však také žen, které by měly být zvláště ostražité kdykoli mají podezření, že muž který o ně projevuje zájem je homosexuál, bisexuál, nebo má někdy homosex za peníze. Důsledky jsou jasné i pro případné dárcovství krve nebo jiných orgánů homosexuály.

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[/img]

[b]Здравствуйте #uname![/b]

Я сама не по наслышке знаю, что такое нужда, когда хочешь, что-то научиться делать, чтобы заработать, а не получается.
Интернет кишит многочисленными экспертами, которые советуют, настоятельно рекомендуют свои чудо способы и возможности по быстрому и легкому заработку.
Я это уже прошла, история стара, как мир. Вы ведётесь на рекламное предложение, получить волшебную кнопку и в одно мгновенье стать богатым.
Но на деле, купив очередное волшебное средство и изучив способ понимаете, что вас в очередной раз развели на деньги и всё.

[url=http://inforabota.tk]Я сама применяю эти три способа они простые и надёжные, посмотреть здесь[/url]

- Сегодня я хочу предложить вам решение ваших проблем, только если вы серьёзно желаете изменить свою жизнь к лучшему и хотите научиться зарабатывать деньги.
- Здесь нет ничего волшебного, этот путь прошли многие люди, которые серьёзно отнеслись к возможностям интернета, чтобы начать работать и зарабатывать.

Способы, о которых пойдет речь может освоить любой простой человек, не имеющий особых знаний и опыта работы в интернете для работы необходимо только иметь:
- серьёзное желание работать
- компьютер и интернет

В дальнейшем, как и в обычной жизни вы наберётесь опыта работы в интернете, если вы совсем новичок и сможете автоматизировать многие процессы, что позволит вам работать меньше а зарабатывать больше.
- Я подчеркиваю - это все три способа работающие, но вам необходимо будет работать, а не просто нажимать одну единственную кнопку " БАБЛО ", здесь такого нет, если вы это ищете, то нам с вами не по пути.

- Сама я уже освоила два способа, набираюсь опыта приобретаю знания и автоматизирую их, пока мои заработки, не очень меня устраивают:
--- первый способ приносит мне от 650 до 850 рублей ежедневно
--- второй способ принес мне например вчера 1439 рублей
--- третий только попробовала, хочу сначала хорошо разобраться с первыми двумя

Я считаю это лучше, чем ничего и второе преимущество - мне искать и покупать ничего больше не нужно.
Спокойно работаю, волнение прошло, в моей жизни наступила полоса спокойствия и увлеченной работы, которая принорсит прибыль постоянно.

Почему я это пишу вам, просто я открыла себя один маленький секрет, и хочу поделиться им с вами.
- Чтобы зарабатывать деньги в интернете - многие люди ищут чудо способ, который позволит им это сделать легко и быстро, а на самом деле просто теряют свои последние деньги и надежду.
- А решение тоже очень простое:
- Чтобы зарабатывать в интернете необходимо - научиться работать в интернете, найти для себя интересное занятие, которое и будет приносить вам постепенно развивающийся и надёжный доход.

[url=http://inforabota.tk]Я его уже нашла, это здесь[/url]

Кто хочет, следуй за мной, всем желаю успеха и найти себе занятие приносящее, настоящее удовольствие и хорошую прибыль.
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01.03.2017 всем пока с вами была Еллиза

926)  Bransonspeah (02.03.2017 11:41)

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