Papilomaviry (HPV) u homosexuálů

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Pavel Čermák

Lidské papilomaviry jsou zodpovědné za 90 – 99 % případů rakoviny děložního čípku a 70 – 100 % případů rakoviny konečníku.

Jejich genetická informace je kódovaná v DNA a jsou známé pod anglickou zkratkou HPV (Human papillomavirus).

Dnes jsou zmapované genetické sekvence více než 170 typů lidských papilomavirů, které se dělí do pěti rodů: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus Nupapillomavirus.

Kromě toho bylo zjištěno přinejmenším dalších 200 domnělých typů virů, které teprve čekají na zmapování svého genomu a klasifikaci.

Wikipedie nabízí následující přehled onemocnění způsobených papilomaviry a u nich vždy čísla typů , které je vyvolávají:

 

Onemocnění

Typ HPV

Common warts

2, 7, 22

Plantar warts

1, 2, 4, 63

Flat warts

3, 10, 8

Anogenital warts

6, 11, 42, 44 and others[13]

Anal dysplasia (lesions)

6, 16, 18, 31, 53, 58[14]

Genital cancers

  • Highest risk:[13] 16, 18, 31, 45
  • Other high-risk:[13][15] 33, 35, 39, 51, 52, 56, 58, 59
  • Probably high-risk:[15] 26, 53, 66, 68, 73, 82

Epidermodysplasia verruciformis

more than 15 types

Focal epithelial hyperplasia (oral)

13, 32

Oral papillomas

6, 7, 11, 16, 32

Oropharyngeal cancer

16

Verrucous cyst

60

Laryngeal papillomatosis

6, 11

 

DNA papilomavirů však byla zjištěna také v periferní krvi u 8,3 % zdravých dárců krve.

V další studii (Carlo Foresta) byly bílkoviny HPV nalezeny v lymfocytech Cd20+ a Cd56+ v periferní krvi a spermatu. Nález souvisel s infekcí spermatu papilomavirem typu 16.

Informace o nepřehledném počtu typů lidských papilomavirů a jejich výskytu v různých typech lidských tkání zde uvádím úmyslně, aby bylo jasné, o jak složitou problematiku se jedná a kolik toho ještě zbývá prozkoumat, protože jednotlivé typy virů se geneticky i chováním v organismu poměrně výrazně liší.

Nechci však vyvolávat paniku. S papilomaviry se během života setká každý a velká část z nich je pokládána za neškodné. Lidský organismus se jich většinou dokáže po infekci zbavit sám a vážné onemocnění způsobí jen v některých případech.

Na druhé straně se však nejedná o zanedbatelnou problematiku, jak vidíme z mohutné kampaně podporující očkování proti některým typům papilomavirů. Základní informaci o papilomavirech je možné nalézt například v článku, který napsal MUDr Fait.  http://www.hpv-guide.cz/clanek-mudr-tomas-fait-phd-co-dokazi-lidske-papilomaviry

Papilomaviry u homosexuálů

Výskytem papilomavirové infekce u mužů kteří mají sex s muži (MSM) se zabývá studie, kterou publikoval Stephen Goldstone a další autoři. Průměrný věk byl 22 let a do studie byli úmyslně vybráni muži, kteří nebyli nakaženi HIV (virem AIDS).

Přítomnost typů papilomavirů 6, 11, 16 nebo 18 byla zjištěna u 30 % MSM (mužů kteří mají sex s muži) v porovnání s 8 % heterosexuálních mužů. Tato studie pracovala s mladými muži o průměrném věku 22 let a tak je počet nakažených relativně nízký v porovnání s jinými studiemi.

Peter Newman a spoluautoři provedli metaanalýzu více studií a uvádějí, že anální infekce papilomaviry se vyskytuje u 15 % heterosexuálních mužů, 60 % MSM kteří jsou HIV negativní a téměř 95 % MSM HIV+ (mužů kteří mají sex s muži a jsou nakaženi virem působícím AIDS).

Vysoký výskyt anální infekce HPV souvisí se zvýšeným výskytem rakoviny konečníku, který je u MSM 44krát vyšší, než v běžné populaci. V případě MSM, kteří jsou nakaženi HIV je výskyt rakoviny konečníku dokonce 60krát vyšší.

Infekce papilomaviry, které patří k nejrozšířenějším původcům sexuálně přenosných nemocí, se tedy vyskytuje přibližně čtyřikrát častěji u mužů, kteří mají sex s muži, než u heterosexuálních mužů. Z toho vyplývají podobná varování jako u jiných pohlavních nemocí. Toto varování se týká v první řadě všech mužů, kteří mají někdy sex s jiným mužem (MSM). Týká se však také žen, které by měly být zvláště ostražité kdykoli mají podezření, že muž který o ně projevuje zájem je homosexuál, bisexuál, nebo má někdy homosex za peníze. Důsledky jsou jasné i pro případné dárcovství krve nebo jiných orgánů homosexuály.

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Уголовное наказание грозит трем оперуполномоченным 2-го отдела полиции МУ МВД России "Орехово-Зуево" 1990, 1991 и 1987 годов рождения, сообщает официальный сайт областного ГСУ СК РФ. "Они подозреваются в совершении преступлений, предусмотренных ч. 3 ст.111 УК РФ (умышленное причинение тяжкого вреда здоровью) и ч.3 ст. 286 УК РФ (превышение должностных полномочий с применением насилия)", - говорится в пресс-релизе.

Предварительно установлено, что вечером 11 апреля 2019 года подозреваемые, находясь возле одного из домов по улице Гагарина в Орехово-Зуеве, "из-за внезапно возникших личных неприязненных отношений к 46-летнему мужчине применили к нему физическое насилие, нанеся ему множественные удары ногами и руками в область головы и тела, после чего скрылись с места происшествия".

Потерпевший был госпитализирован в больницу с диагнозом "закрытая черепно-мозговая травма". Спустя неделю он скончался от полученных телесных повреждений.

Подробности случившегося приводит телеграм-канал Mash. По его данным, от рук стражей порядка погиб Сулли Юнусилау, отец двукратного чемпиона мира по ММА Магомеда Юнусилау. У Юнусилау-старшего врачи диагностировали отек и дислокацию мозга, а также сильные гематомы.

По данным Mash, потерпевшего избили оперуполномоченные Дмитрий Блинов, Павел Попов и Олег Шишканов, которые "от нечего делать пристали на улице к мужчине". Полицейские "шутили над его внешностью и пытались задержать" Сулли Юнусилау.

Отец спортсмена забежал в аптеку и попросил продавщицу вызвать полицию, но злоумышленники зашли следом и сказали, что сами из полиции и окажут помощь. На опубликованном видео из аптеки запечатлено, как один из сотрудников МВД показал сотруднице аптеки служебное удостоверение. Прямо в аптеке стражи порядка избили Сулли, а потом поволокли его на улицу.

В рамках расследования взят под стражу только Дмитрий Блинов, а Павел Попов и Олег Шишканов оставлены под домашним арестом.

"В ближайшее время всем троим будет предъявлено обвинение. Планируется назначение психиатрической и генетической экспертиз, а также проведение очных ставок и выход на место происшествия с очевидцами", - подчеркнули в ГСУ СК РФ.

В ГУ МВД Московской области проводят проверку, по результатам которой в случае установления вины полицейских они будут уволены из органов внутренних дел и привлечены к ответственности в соответствии с законодательством, передает ТАСС. Кроме того, к строгой дисциплинарной ответственности будут привлечены их непосредственные руководители, пообещали в полиции.

Сын погибшего Магомед Юнусилау в период с 2015 по 2018 годы провел шесть боев в рамках турниров MMA. Во всех поединках он одержал победу, сообщает Fighttime.

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